Gastrointestinal stromal tumor (GIST) ICD 8936/3

UZLX-GIST9F

(Synonyms: -)

HUSARC Accession Number: HU-23.15

KIT; Exon 11 ; p.P577del & W557LfsX5; Exon 17 D820G (Cosmic: COSM1684822 , COSM1316)

More information about the models can be found in the datasheets.

If you are interested in a model, please contact the corresponding researcher directly (contact information can be found below and in the datasheet).

Cornillie J, Wozniak A, Li H, Wang Y, Boeckx B, Gebreyohannes YK, Wellens J, Vanleeuw U, Hompes D, Stas M, Sinnaeve F, Wafa H, Lambrechts D, Debiec-Rychter M, Sciot R, Schöffski P. Establishment and Characterization of Histologically and Molecularly Stable Soft-tissue Sarcoma Xenograft Models for Biological Studies and Preclinical Drug Testing. Mol Cancer Ther. 2019 Jun;18(6):1168-1178. doi: 10.1158/1535-7163.MCT-18-1045. Epub 2019 Apr 8. PMID: 30962320.
Wang Y, Wozniak A, Wellens J, Gebreyohannes YK, Guillén MJ, Avilés PM, Debiec-Rychter M, Sciot R, Schöffski P. Plocabulin, a novel tubulin inhibitor, has potent antitumor activity in patient-derived xenograft models of gastrointestinal stromal tumors. Transl Oncol. 2020 Nov;13(11):100832. doi: 10.1016/j.tranon.2020.100832. Epub 2020 Jul 22. PMID: 32711367; PMCID: PMC7381700.

Entry creation: 14.09.2021

Last entry update: 16.09.2021

Version number: #1