Gastrointestinal stromal tumor (GIST) ICD 8936/3

GIST-T1

(Synonyms: GIST-T-1 ; GISTT1 ; T1)

HUSARC Accession Number: HU-21.1

KIT; Exon 11 ; p.Val560_Tyr578del (c.1679_1735del); Zygosity=Heterozygous

GEO accession GSE95861 (Illumina NextSeq 500)
GEO accession GSE95862 (Illumina NextSeq 500)
GEO accession GSE69465 (Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray)

More information about the models can be found in the datasheets.

If you are interested in a model, please contact the corresponding researcher directly (contact information can be found below and in the datasheet).

Taguchi T, Sonobe H, Toyonaga S, et al. Conventional and molecular cytogenetic characterization of a new human cell line, GIST-T1, established from gastrointestinal stromal tumor. Lab Invest. 2002;82(5):663-665. DOI:10.1038/labinvest.3780461 / PMID:12004007

Grunewald S, Klug LR, Mühlenberg T, et al. Resistance to Avapritinib in PDGFRA-Driven GIST Is Caused by Secondary Mutations in the PDGFRA Kinase Domain. Cancer Discov. 2021;11(1):108-125. DOI:10.1158/2159-8290.CD-20-0487 / PMID: 32972961

Entry creation: 23.08.2021

Last entry update: 16.09.2021

Version number: #1